Biomimetic microenvironments for regenerative endodontics

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Biomimetic microenvironments for regenerative endodontics

Regenerative endodontics has been proposed to replace damaged and underdeveloped tooth structures with normal pulp-dentin tissue by providing a natural extracellular matrix (ECM) mimicking environment; stem cells, signaling molecules, and scaffolds. In addition, clinical success of the regenerative endodontic treatments can be evidenced by absence of signs and symptoms; no bony pathology, a dis...

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Stem Cells in Regenerative Endodontics

Background Currently, clinical endodontics includes procedures that are based on the ability of stem cells to accomplish repair (eg, direct pulp capping, apexogenesis, apexification, and even pulpal regeneration). An attempt is made to critically assess the current status in pulp regeneration therapy. Methods: Systematically, 2 distinctly different strategies exist involving stem cells for t...

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Scaffolds in regenerative endodontics: A review

Root canal therapy has enabled us to save numerous teeth over the years. The most desired outcome of endodontic treatment would be when diseased or nonvital pulp is replaced with healthy pulp tissue that would revitalize the teeth through regenerative endodontics. 'A search was conducted using the Pubmed and MEDLINE databases for articles with the criteria 'Platelet rich plasma', 'Platelet rich...

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Regenerative Endodontics: An Evidence Based Review

Endodontic treatment of a tooth in its present state offers a high degree of success for most cases, but it leaves the tooth in a physiologically “dead” state. Regenerative endodontics is an emerging field which is trying to regenerate natural tissues associated with the tooth generated by nature. This article reviews the present status of regenerative endodontics, why is it important to regene...

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ژورنال

عنوان ژورنال: Biomaterials Research

سال: 2016

ISSN: 2055-7124

DOI: 10.1186/s40824-016-0061-7